What are the functions and functions of rivaroxaban tablets?
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What are the functions and functions of rivaroxaban tablets?
![What are the functions and functions of rivaroxaban tablets? 202211280928506d4ca781fbd74e9286271ee68c9c7415](https://www.arshinepharma.com/Content/uploads/2022695992/202211280928506d4ca781fbd74e9286271ee68c9c7415.png)
Rivaroxaban is a new type of anticoagulant drug, it is a factor Xa inhibitor, and it is a more commonly used anticoagulant drug in clinical practice. In the past, the most common oral anticoagulant drug was warfarin, but due to the need for frequent monitoring of coagulation , and the risk of bleeding is relatively high, and the probability of major bleeding is relatively high, especially prone to cerebral hemorrhage and gastrointestinal bleeding, which can be life-threatening in severe cases. Therefore, it is considered to replace warfarin with rivaroxaban in recent years, especially for Anticoagulants for deep vein thrombosis, pulmonary embolism, and thrombosis in nonvalvular atrial fibrillation. Rivaroxaban is taken orally once a day , and does not require frequent monitoring of coagulation, especially because the chance of bleeding is relatively low. It has been reported in the literature that rivaroxaban has a certain effect on the recurrence rate of deep vein thrombosis and pulmonary embolism, compared with warfarin Reduction of recurrence rate can be as high as 50%.
Rivaroxaban Tablets is an oral bioavailable factor Xa inhibitor, which can selectively block the active site of factor Xa, and does not require cofactors, such as antithrombin III, to exert its activity , which activates factor X to factor Xa through intrinsic and extrinsic pathways, and plays an important role in medical measurement responses. Rivaroxaban dose-dependently inhibits the activity of factor Xa in humans. The prothrombin time measured by some reagents, the activated partial prothrombin time and the quantitative monitoring of heparin can be seen to prolong dose-dependently. The same is true for the activity of factor Xa. Under the influence of rivaroxaban. In clinical practice, rivaroxaban tablets are mainly used in diseases that prevent thrombosis or after surgery.
Rivaroxaban tablets have certain adverse reactions, such as bleeding, and there are risks of bleeding in various parts, such as gum bleeding, nose bleeding, skin ecchymosis, gastrointestinal bleeding, cerebral hemorrhage, etc., and severe cases may be life-threatening. Contraindications of rivaroxaban: Patients with various bleeding risks, patients with gastrointestinal bleeding, cerebral hemorrhage, and coagulation disorders should not take it orally, and patients with severe liver insufficiency and renal insufficiency should not take it orally.
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